Only medicines with a known interaction with nirmatrelvir plus ritonavir are listed. If a medicine is not listed below it cannot automatically be assumed it is safe to co-administer.

IMPORTANT INFORMATION

This checker was developed for the Australian veteran population and may not be universally applicable. This page was last updated on 09/08/2022.

The suggested actions and clinical comments are based on available information sources including the Australian Product Information, available at the Australian Register of Therapeutic Goods Website, the Liverpool COVID-19 Interactions Checker, the Ontario COVID-19 Science Advisory Table and the NIH Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid®) and the Concomitant Medication . For some medicines, data on nirmatrelvir plus ritonavir interaction is limited.

Contraindicated (Red) - For these medicines, there is a risk of serious side effects or reduced treatment efficacy. Do not co-administer with nirmatrelvir plus ritonavir.

Attention required (Orange) - There is potential interaction with nirmatrelvir plus ritonavir, and clinical evaluation of current therapy is recommended.

Follow up (Grey) - The potential interaction usually does not require pre-emptive therapy change, but should be monitored over time.

No known interaction (Green) - No interaction between this medicine and nirmatrelvir plus ritonavir is expected.

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